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However, little is famous concerning the natural history of preclinical DCIS in the absence of biopsy or complete excision. Methods Two well-established populace models evaluated six possible DCIS normal history submodels. The submodels thought 30%, 50%, or 80% of breast lesions progress from invisible DCIS to preclinical screen-detectable DCIS; each design furthermore permitted or prohibited DCIS regression. Preclinical screen-detectable DCIS ma