https://www.selleckchem.com/pr....oducts/bsj-03-123.ht
MiR-30b-5p up-regulation increased the levels of MMP-13 and cleaved caspase-3, but decreased those of Aggrecan and COLII in chondrocytes. However, the action of miR-30b-5p up-regulation on chondrocytes was reversed by Hoxa1 overexpression. In conclusion, miR-30b-5p is involved in cartilage degradation in rats with chronic exercise arthritic injury and regulates chondrocyte apoptosis and migration by targeting Hoxa1. 1 ESGE recommends placement of partially or fully covered self-expandable metal stents (SEMSs) for palliation of malign