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Moreover, the interaction of health-promoting lifestyle and eHealth literacy negatively predicted cognitive health (β = -0.465, p less then 0.01). Conclusions Health-promoting lifestyles and eHealth literacy were associated with the cognitive health of Chinese older adults, both independently and interactively. Further, eHealth literacy was associated with health-promoting lifestyles in older adults. Therefore, interventions regarding healthy lifestyles and eHealth literacy would benefit older adults.The aim of the study was to analyze