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Results.All isodose volumes greater than 10% of the prescription dose decreased with decreasing MAD in all comparisons. In the range of 10% to 100% of the prescription dose, the rate of isodose volume decrease was exponential as a function of MAD in all comparisons. Reduction of absolute isodose volume is seen with increased 4πsampling, with larger target volumes exhibiting larger absolute reductions. Very low isodoses (0% to 10% of prescription) increased with decreasing MAD.Conclusions.MAD is a 4πsampling quantity useful in quantifyin
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