https://www.selleckchem.com/pr....oducts/gsk2879552-2h
What is the relationship between sperm DNA fragmentation and oxidative stress (OS) with increasing male age? Sperm DNA fragmentation increases with age and is likely related to both defective spermatogenesis and increasing OS levels. Sperm quality declines with age. The presence of DNA damage in a high fraction of spermatozoa from a raw semen sample is associated with lower male fertility in natural conception and intrauterine insemination. A retrospective cohort study of 16 945 semen samples analysed at a single reference labor