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994. Plasma clearances of Cr-EDTA and Tc-DTPA were 66.1 ± 25.8 and 68.1 ± 26.6mL/min, respectively, with a mean bias of 1.96 ± 3.32mL/min, an accuracy within 10% of 91% [95% CI 85-97] and a R of 0.985. Distribution volumes were 17.3 ± 4.6 L for Cr-EDTA and 16.6 ± 4.6 L for Tc-DTPA (R 0.93. The accuracy and precision of Tc-DTPA clearance, compared to Cr-EDTA clearance, was excellent for both urinary and plasma clearance methods, despite an approximate 2mL/min overestimation, showing that the tracer is a reliable alternative to Cr-EDTA