https://www.selleckchem.com/pr....oducts/pi3k-hdac-inh
CONCLUSIONS In this study, we identified a plausible new candidate gene ADCY9 of CHD through the clinical and genetic analysis of a rare case of Rubinstein-Taybi (RT) syndrome with serious cardiac abnormalities. By functional study of zebrafish, we demonstrated that deletion of adcy9 is the causation for the cardiac abnormalities. Cardiac apoptosis and increased expression of the MMP9 gene are involved in the pathogenesis.BACKGROUND Human obesity is linked with systemic inflammation. However, it is still controversial if e
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