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The TCD value, ICP, and prognosis were compared between the 2 groups. The average postoperative ICP 19 mmHg in the first 24 h, mean blood flow velocity 56.33 cm/s, end-diastolic blood flow velocity 40.28 cm/s, and resistance index 0.57 were statistically significant indicators to predict good prognosis . The use of TCD can predict the prognosis of severe craniocerebral injury patients. The use of TCD can predict the prognosis of severe craniocerebral injury patients. Reduning injection is a traditional Chinese medicine (