https://www.selleckchem.com/pr....oducts/gusacitinib.h
Moreover, the apoptosis was alleviated when cells were pretreated with PJ34 hydrochloride (PARP1 inhibitor), suggesting the mitochondrial PARP1 dependent pathway played a pivotal role in L02 cells apoptosis. This study indicated that PARP1 was an important molecular target in this process. And it also helped to understand the mechanism of hepatocytes apoptosis, early hepatic toxicity, and even liver diseases.Zika virus (ZIKV) can infect developing fetuses in utero and cause severe congenital defects independent of route of maternal