https://www.selleckchem.com/pr....oducts/chk2-inhibito
High activity of Indoleamine 2,3-dioxygenase1 (IDO1) in lung cancer patients converts tryptophan (Trp), which is the essential amino acid for T-cell metabolism, to kynurenine (Kyn) and consequently suppresses anti-tumor immune responses. We aimed to track the dynamics of IDO1 activity in stage III non-small cell lung cancer (NSCLC) patients who received first-line radiotherapy (RT) and explore its association with survival outcomes. Systemic IDO1 activity was calculated by Kyn Trp ratio. Plasma levels of Kyn and Trp in
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