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On Cox regression analysis, PNI 44, MELD score, TNM staging, synthetic colloid use, and transfusion were associated with poorer 5-year survival. NRI analysis showed significant improvement in the predictive power of PNI for transfusion ( = 0.002) and 5-year survival ( = 0.004). Preoperative PNI 44 was significantly associated with higher transfusion rates and surgical outcomes. Preoperative PNI less then 44 was significantly associated with higher transfusion rates and surgical outcomes.Complications in megaprosthetic reconstruc