https://www.selleckchem.com/products/mhy1485.html
The 15-nm SiO NPs were found to have higher cytotoxicity than the larger NPs. Notably, the 15-nm SiO NPs induced retinal toxicity in vivo, as demonstrated by increased cell death in the retina, TUNEL-stained retinal cells, retinal ganglion cell degeneration, glial cell activation, and inflammation. In addition, The SiO NPs caused oxidative stress, as demonstrated by the increase in the ROS indicator H DCF-DA. Furthermore, the pretreatment of R28 cells with N-acetylcysteine, an ROS scavenger, attenuated the ROS production and cytotoxicit
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