https://www.selleckchem.com/pr....oducts/Rapamycin.htm
Occlusive thrombi are not homogeneous in composition. The core of a thrombus is rich in activated platelets and fibrin while the outer shell contains resting platelets. This core is inaccessible to plasma proteins. We produced a fusion protein (targeted SERPIN-TaSER), consisting of a function-blocking V H against glycoprotein Ibα (GPIbα) and a thrombin-inhibiting serine protease inhibitor (SERPIN; α1-antitrypsin AIAR ) to interfere with platelet-driven thrombin formation. To evaluate the antithrombotic properties of TaSER. Besides TaS
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