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Outcomes BM-MSC showed much better possible, increased corneal markers, and higher transepithelial electric opposition values whenever caused with limbal epithelial culture medium. Induced BM-MSC promoted better wound recovery of real human corneal epithelial cells by paracrine secretion. Conclusion BM-MSC has potential for corneal epithelial induction in a protocol suitable for real human application.Refractory gout (RG) was progressively proven to be a problem in medical treatment. Clients clinical