https://www.selleckchem.com/pr....oducts/mi-773-sar405
Genome-wide association studies (GWAS) have revealed multiple loci associated with atopic dermatitis (AD). Some have confirmed pre-existing knowledge, including the role of skin barrier and type 2 inflammation in AD pathogenesis, whilst others have provided newer insights, including evidence of auto-immunity and previously unrecognized genes controlling epidermal differentiation. The majority of risk loci are in intergenic regions for which functional mechanism(s) remain unknown; these loci require detailed molecular studies, c
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