https://www.selleckchem.com/products/sbe-b-cd.html
The baseline renal graft level (E, maximum effect (Emax), AUC achieving 50% of the maximum effect (EAUC5, and nephrotoxicity slope were estimated as 12.9 mL/min/1.73 m2, 50.7 mL/min/1.73 m2, 1740 ng.h/mL, and 0.00033, respectively. Hemoglobin level was identified as a significant covariate affecting the E0. The model discerned acute rejection from nephrotoxicity in 19/24 cases. A time-dissociated PKPD model successfully described a large number of observations and was used to develop an online tool to predict renal graft response.
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