https://www.selleckchem.com/pr....oducts/Rapamycin.htm
01). Compared with blank control group, the model group had obviously increased content of TNF-α and IL-6 (P less then 0.01), decreased content of IL-10 (P less then 0.01), more apoptotic neurons (P less then 0.01), higher expression of caspase-3 (P less then 0.01), and obviously lower Bcl-2/Bax (P less then 0.01). Moreover, expression of phosphorylated (p)-PTEN, PI3K and p-Akt in brain tissues was remarkably lower in the model group than those in the blank control group (P less then 0.01). The expression level of miR-130a in brain ti
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