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Osteosarcoma, Ewing sarcoma and chondrosarcoma tend to be uncommon diseases but the most common primary tumors of bone tissue. The genetics right mixed up in sarcomagenesis, tumor development and therapy responsiveness are not entirely defined for these tumors, in addition to effective breakthrough of genetic analysis is highly warranted within the view of enhancing the treatment and cure of clients. The analysis summarizes recent advances in regards to the molecular and genetic backgrou