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All the designed compounds showed proper and stable chemical interactions with gp41 according to the in silico studies. The results of the biological tests proved none of the compounds active against HIV-1 replication in cell cultures. Since all the studied compounds were potently toxic for the host cell; it was therefore not possible to assess their anti-HIV activities. Since all the studied compounds were potently toxic for the host cell; it was therefore not possible to assess their anti-HIV activities. Toxoplasmosis is still a neglec
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