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Significant deviations from the standard model are observed in semileptonic charged and neutral-current B decays, the muon magnetic moment, and the extraction of the Cabibbo angle. We propose that these deviations point towards a coherent pattern of new physics effects induced by two scalar mediators, a leptoquark S_1 and a charged singlet ϕ^+. While S_1 can provide solutions to charged-current B decays and the muon magnetic moment, and ϕ^+ can accommodate the Cabibbo-angle anomaly independently, their one-loop level synergy can also a