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5%, 100%, and 97.9%, respectively. Moreover, BWF showed a higher sensitivity in EGFR mutation testing than both plasma (100% [8/8] vs. 62.5% [5/8], = 0.095) and bronchoscopy biopsy samples (92.5% [37/40] vs. 77.5% [31/40], = 0.012) and identified EGFR mutations in 6 cases whose biopsy failed to establish an LC diagnosis. The diameter of the target lesion and its contact degree with BWF were positive predictive factors for EGFR testing results. BWF yields a high sensitivity in EGFR mutation testing, having high concordance with histologic