https://www.selleckchem.com/pr....oducts/Nafamostat-me
Tetrahydroquinolines (THQs), a class of nonsteroidal ecdysone agonists, are good candidates for novel mosquito control agents because they specifically bind to mosquito ecdysone receptors (EcRs). We have recently performed quantitative structure-activity relationship (QSAR) analyses of THQs to elucidate the physicochemical properties important for the ligand-receptor interaction. Based on previous QSAR results, here, we newly synthesized 15 THQ analogs with a heteroaryl group at the acyl moiety and evaluated their binding af
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