https://www.selleckchem.com/pr....oducts/chk2-inhibito
Taking the β-Hex release rate of the model group as the base, the release rate of SD and POG in high dose groups were 43.79% and 57.01%, respectively, which were significantly lower than model group ( 0.01), and significantly lower than KF group (63.83%, 0.01, 0.05). SD and POG could down-regulate the expression of related proteins in the Lyn/Syk, PI3K/AKT and MAPK signalling pathways. could inhibit IgE-induced degranulation of mast cells, providing a scientific basis for further research and clinical
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