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Many paths were proven to donate to migration and invasion of malignant tumors. Aspartate β-hydroxylase (ASPH) is a key player into the malignant transformation of solid tumors by boosting cell proliferation, migration, and invasion. ASPH additionally promotes tumefaction development by stimulation of angiogenesis and immunosuppression. These results tend to be primarily attained through the activation of Notch and SRC signaling paths. ASPH appearance is upregulated by development facets a