https://www.selleckchem.com/pr....oducts/gsk2141795.ht
This TAFA4-IL-10 axis also ensures the survival and maintenance of IL-10+TIM4+ dermal macrophages, reducing skin inflammation and promoting tissue regeneration. These results reveal a neuroimmune regulatory pathway driven by the neuropeptide TAFA4 that promotes the anti-inflammatory functions of macrophages and prevents fibrosis after tissue damage, and could lead to new therapeutic perspectives for inflammatory diseases.Ubiquitylation is a widespread post-translational protein modification in eukaryotes and marks bacteria that invad
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