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https://teniposideinhibitor.co....m/microrna-1388-5p-i
Consistent with these results, Puf2 contains several low-complexity and intrinsically disordered protein regions with a tendency to form aggregates and, whenever over-expressed, represses translation to induce aggregation of poly(A) binding protein Pabp, the trademark constituent of SGs. Intriguingly, over-expression of Puf2 also improves the structure of handling bodies (PBs), another type of cytoplasmic RNA granules, a complex of aspects involved in mRNA degra