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This paper deals with the anti-synchronization issue for stochastic delayed reaction-diffusion neural networks subject to semi-Markov jump parameters. A resilient fault-tolerant controller is utilized to ensure the anti-synchronization in the presence of actuator failures as well as gain perturbations, simultaneously. Firstly, by means of the Lyapunov functional and stochastic analysis methods, a mean-square exponential stability criterion is derived for the resulting error system. It is shown the obtained criterion improves a previously