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Culturing HSCs/HPCs in physioxia is an enhanced method of effective progenitor T and mature T-cell production ex vivo and may be of future use for HCT and T-cell immunotherapies.The generation of different thermodynamically (meta)stable states is crucial for the development of smart solid-state luminescent materials. However, the design of luminophores with tunable aggregation states is remaining a grand challenge. Herein, we present a family of mechanochromic luminophores with tunable metastable states, based on the dynamically contro