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Novel psychoactive substances (NPS) continue to represent a threat to public health and safety. The number of new drugs in the latest emergent synthetic opioid class - the 2-benzylbenzimidazole analogues - also called the nitazenes - have begun to dominate the current novel synthetic opioid (NSO) subclass of NPS. We describe a liquid chromatography tandem quadrupole mass spectrometry (LC-QQQ-MS) method for the quantification of nine analogues and/or metabolites of drugs in this series isotonitazene, metonitazene, protonitazene, etonitazen
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