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Low back pain was found to be a frequent occurrence in young adults and it was more prevalent in those using firm or foam mattresses for more than three years. To determine the effect of blood flow restriction with strengthening exercises on knee osteoarthritis patients. The case-control study was conducted at the Department of Physical Medicine and Rehabilitation, Combined Military Hospital, Okara, Pakistan, from June to December 2018, and comprised knee osteoarthritis patients who were assigned to two equal groups. The cases in Group