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Moreover, these changes correlate with the main histological features steatosis, apoptosis, iron deposits and fibrosis. Strikingly, treatment with the repurposed drug ciclopirox improves the phosphoromic profile of CEP mice, an effect that was mirrored by the normalization of liver histology. In conclusion, these findings indicate that NMR-based phosphoromics may be used to unravel metabolic phenotypes of liver injury and to identify the mechanism of drug action.Chemical weed control has been widely adopted and has led to increased effic