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In this category it outperforms existing tools, especially when tested on large datasets of archaeal and bacterial genomes. We provide digIS, a software tool using a novel approach based on manually curated profile hidden Markov models, which is able to detect distant and putative novel IS elements. Although digIS can find known IS elements as well, we expect it to be used primarily by scientists interested in finding novel IS elements. The tool is available at https//github.com/janka2012/digIS. We provide digIS, a software tool using a n
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