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Collectively, our present results show the feasibility of FEXI in calculating different liquid change processes in vivo, and that FEXI concentrating on the vascular water may help define the intra-to-extravascular water change process.Background Extracellular free water within cerebral white matter tissue has been confirmed to boost with age and pathology, however the intellectual effects of no-cost liquid in typical ageing prior to the development of neurodegenerative illness