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Of this 42 clients which did not satisfy Howard criteria for TLS, isolated hyperphosphatemia occurred in 19 clients (45%), hyperkalemia in 13 clients (31%), hyperuricemia in 2 patients (5%), and hypocalcemia in 1 client (2%). In routine rehearse, the occurrence of TLS appears higher than reported in clinical studies (3-6%). 50 % of customers whom failed to meet criteria for TLS created medically considerable electrolyte abnormalities that needed health intervention.Background Orb
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