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The meta-analysis revealed that Internet-based psycho-educational treatments had an important effect on decreasing depression (standardized mean difference (SMD) - 0.58, 95% self-confidence period (CI) (- 1.12, - 0.03), p = 0.04) and weakness (mean distinction (MD) - 9.83, 95% CI (- 14.63, - 5.03), p less then 0.01). But, there was no evidence for results on distress (SMD - 1.03, 95% CI (- 2.63, 0.57), p = 0.21) or quality of life (MD 1.10, 95% CI (- 4.42, 6.63), p = 0.7. CONCLUSION Internet-based p