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In this respect, this work geared towards creating brand-new thermosensitive micellar hydrogels beginning with a custom-made amphiphilic poly(ether urethane) (PEU). Particularly, a commercial triblock copolymer (Poloxamer® 407), chosen to guarantee the temperature-driven chain arrangement into micelles, had been reacted with 1,6-diisocyanatohexane and 1,4-cyclohexanedimethanol. The successful PEU synthesis had been shown by size-exclusion chromatography ( M ¯ w 50000 Da) and infrared spectroscopy. Later, the wettability-drive