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38 μg/ml) D0 (0.49 μg/ml) D1 (0.24 μg/ml) in pigs and D0 (1.55 μg/ml) D2 (0.27 μg/ml) in chickens. The longer t 1/2 (elimination half-life) of D0 contributed to the slow elimination of DVD-related compounds. The t 1/2β of D0 in pigs (66.41 h) was significantly longer than that in chickens (48.30 h), but the t 1/2 of total DVD-related metabolites in pigs (42.86 h) was lower than that in chickens (56.11 h). These findings suggested that the metabolism and pharmacokinetics of DVD in pigs and chickens were significantly diffe