https://www.selleckchem.com/pr....oducts/pf-4708671.ht
Aim Explore the possible association between clinical factors and genetic variants of the dopamine pathways and negative symptoms. Materials methods Negative symptoms were assessed in 206 patients with schizophrenia using the Arabic version of the self-evaluation of negative symptoms scale and the Positive and Negative Syndrome Scale. Genotyping for COMT, DRD2, MTHFR and OPRM1 genes was performed. Results Multivariable analysis showed that higher self-evaluation of negative symptoms scale scores were significantly associated wi