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05). The median DI values of the GTV and GTV in the GTV were 0.82 and 0.86, respectively ( = 0.006). The median CI values of the GTV in the GTV and GTV were 0.68 and 0.72, respectively ( = 0.006). PET/CT can be used to optimize the definition of the target volume in EC. However, no significant difference was found between the GTVs delineated based on visual referencing or deformable registration whether using the volume or position. So, in the absence of planning PET-CT images, it is also feasible to delineate the GTV of primary thoraci