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Using this approach, 723.5 mg/L 4-HBA, 942.0 mg/L DHB, and 347.7 mg/L MP were synthesized. Our study showed that the shikimate gene module constructs can be applicable to increase the yields of HBA derivatives in HBA-tolerant microorganisms.A high-resistant starch (RS) and low-glutelin diet is beneficial for the health of patients with diabetes and kidney diseases. Rice is an important food crop worldwide. Previous studies have demonstrated that downregulating the expression of rice starch branching enzyme IIb (SBEIIb) affected the com