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2, the value is 0.007. The difference is statistically significant at 0.05. Postmenopausal women were more likely to expire due to COVID-19 infection compared to premenopausal women. The mortality rate in postmenopausal age group was greater than mortality in premenopausal females emphasizing the protection provided by estrogens hormone in them. Postmenopausal women are also at higher risk of severe COVID-19 infection than premenopausal women. Mortality is greater in males compared to females, further strengthening the role of estro