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A rapid and accurate method to identify the species and antibiotic resistance of Candida in blood is vital to increase the survival rates of patients with bloodstream infections. However, the extremely low levels of Candida in blood make rapid diagnosis by standard blood culture difficult. In this study, we constructed a direct blood culturing method (i.e., the M1 method) by a rapid enrichment method with magnetic beads coated with a recombined human mannan-binding lectin (rhMBL, i.e., M1 protein), which demonstrated much higher Candida-