https://rnr-receptor.com/index.....php/structurel-cons
To demonstrate the feasibility of the method, we have made use of the antihistamine agent loratadine (1). Twenty-six analogues of loratadine were isolated and completely described as NMR. Informative SAR analogues were identified, which display powerful affinity for the real human histamine H1 receptor and improved metabolic stability.We present a purely mechanistic model to anticipate protonophoric uncoupling activity ECw of organic acids. All needed input
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