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0 mg (IQR 2.0-21.3) vs 12.0 mg (IQR 8.0-22., p= ), as well as the incidence of severe pain during the 24 hours of follow-up (4.0% vs 22.8%, p0.01). The mandibular block had no impact on the incidence of PONV. Bilateral V3 block for mandibular osteotomies is an effective opioid-sparing procedure. It provided better postoperative analgesia in the first 24 hours, and it did not affect PONV incidence. NCT02618993. NCT02618993.Skeletal muscle channelopathies are a group of rare episodic genetic disorders comprising the periodic paral