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The Editors of JBUON issue an Expression of Concern to 'Heptaphylline suppresses the proliferation and migration of human bladder cancer cells via induction of intrinsic apoptosis, autophagy and inhibition of β-catenin signalling pathway', by An Xu, Gang-Gang Yang, Yu Zhang, Shu-Tian Zhao, JBUON 2020;25(1)274-279; PMID 32277642. Following the publication of the above article, readers drew to our attention that part of the data was possibly unreliable. We sent emails to the authors with a request to provide the raw data to prove the orig