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ems, and undergo thorough examination of resultant offspring in preclinical models before utilization. Our results using in-vitro systems for oocyte maturation in both mouse and human provide proof of principle that mitochondrially targeted molecules such as MitoQ and BGP-15 may represent a novel therapeutic approach against maternal aging-related spindle and chromosomal abnormalities. The project was financially supported by the National Health and Medical Research Council and Australian Research Council, Australia. U.A.-Z. was supporte
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