https://www.selleckchem.com/pr....oducts/pyrrolidinedi
We found that the AD group had lower CSF concentrations of Aβ1-42 (p 0.001) and calcium (p 0.001), but a higher CSF concentration of iron (p 0.001). Significantly lower plasma concentrations of ceruloplasmin (p = 0.003), transferrin (mean, p 0.001), and iron (p 0.001) were observed in the AD group than in cognitively normal adults. Moreover, we found a strong interdependence between most of these components. Iron dyshomeostasis has a crucial role in the onset of AD and/or its