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The damage of glaucoma has been extensively evaluated at the level of retina and optic nerve head. Many advances have been shown in this field in the last decades. Recent studies have also proved degenerative changes in the brain involving intracranial optic nerve, lateral geniculate nucleus, and visual cortex. Moreover, these brain abnormalities are also correlated with clinical, optic nerve head, and visual field findings. In this review, we critically evaluate the existing literature studying the use of magnetic resonance imaging in