https://www.selleckchem.com/pr....oducts/elimusertib-b
We showed that the antiviral and antitumorigenic isoprenoid compound ascochlorin increased MBNL1 and hnRNP L expression levels. Drug treatment of DM1 muscle cells with ascochlorin partially rescued missplicing of established early biomarkers of DM1 and improved the defective myotube formation displayed by DM1 muscle cells. Together, these studies revealed that hnRNP L can modulate DM1 pathologies and is a potential therapeutic target. Together, these studies revealed that hnRNP L can modulate DM1 pathologies and is a po
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