https://www.selleckchem.com/pr....oducts/cd38-inhibito
Our results suggest that PD-1-anergy is a common feature of NSCLC immune responses, whereas PD-1-mediated immune suppression is present only in a minority of patients. The latter was associated with poor clinical outcomes in our sample. Conclusions Overall, our results indicate that bystander suppression or the 'anergy-only' phenomenon may be novel biomarkers in NSCLC and suggest prediction value based on these phenotypes.Excessive cytokine signaling frequently exacerbates lung tissue damage during respiratory viral infection.